| Diagnosis |
Investigator/Sponsor |
Protocol Title & Purpose |
Eligibility |
| Thoracoabdomnal aneurysm |
W. Anthony Lee, MD, FACS
NCT01524211
|
Physician-Sponsored IDE:"Evaluation of Branch Endografts in the Treatment
of Aortic Aneurysms" |
- Adult, 18 years and older
Patient must have one of the following:
- Degenerative, atherosclerotic thoracoabdominal, suprarenal and juxtarenal
aortic aneurysms (fusiform or saccular): ≥55 mm in diameter in a male
or ≥ 50 mm in diameter in a female, or
- Thoracoabdominal aortic aneurysm with a history of growth ≥ 0.5 cm per year, or
- Penetrating ulcers: ≥ 20 mm in depth, or
- Chronic type B aortic dissections: ≥ 50 mm total aortic diameter, or
- Symptomatic pathology (aneurysm, ulcer or chronic dissection) of any size.
- Additional criteria for LP material: Iliofemoral access vessels < 8
mm or with significant atherosclerotic occlusive disease that would require
an iliac conduit as determined by the PI.
|
| Infrarenal Abdominal Aortic Aneurysms |
Bolton Medical, Inc
NCT02009644
|
IP-0008-12 A Phase II Clinical Study of the Safety and Performance of the
Treovance Stent-Graft with Navitel Delivery System for Patients with Infrarenal
Abdominal Aortic Aneurysms |
- Between the ages of 18 and 85
- Diagnosed with an infrarenal abdominal aortic aneurysm (AAA), with or without
iliac artery involvement
- Infrarenal AAA that is ≥ 4.5 cm in diameter for mails, or ≥ 4.0 cm
in diameter for females, or has increased in diameter by 0.5 cm in the
last 6 months
- Infrarenal landing neck length of 10 mm or greater and angle of less than
60 degrees relative to long axis of aneurysm, or
- Infrarenal landing neck length of 15 mm or greater and angle of between
60 and 75 degrees relative to long axis of aneurysm and suprarenal neck
angle of less than 45 degrees relative to the infrarenal neck axis and
an outside diameter of 16 mm-30 mm
- Infrarenal landing neck must meet the vessel size requirements specified
in the instructions for use
- Lowest renal artery at least 9 cm from the aortic bifurcation
- Iliac landing neck with inside diameter of 8 mm - 13 mm and a length of
at least 10 mm, or inside diameter of >13 mm - 20 mm and a length of
at least 15 mm
- Distal iliac landing neck must meet the vessel size requirements specified
in instructions for use
- Total treatment length of at least 13 cm
- Distal aortic diameter above the iliac bifurcation equal to or greater
than 70% of the sum of the selected leg graft diameters.
- Willing and able to comply with 1-month, 6-month, and 12-month follow-up
visits, and annual visits out to 5 years
- Adequate renal function to tolerate contrast enhanced CT
- Adequate vascular access or introduction of Navitel Delivery System or
anatomy is suitable for creation of iliac conduit
|
| Juxtarenal aortic aneurysms |
Cook Incorporated
NCT02396199
|
Evaluation of the safety and effectiveness of the Zenith p-Branch in combination
with Atrium iCAST covered stents for the treatment if paraenal or juxtarenal
aortic aneurysms. |
- Pararenal or juxtarenal AAA ≥ 5.0 cm in diameter or 2X normal aortic
diameter,or
- Pararenal or juxtarenal AAA with history of growth ≥ 0.5 cm/year, or
- Saccular aneurysm with aortic diameter < 1.5X normal aortic diameter
deemed at risk for rupture by physician
|
| Aneurysm iliac arteries |
Cook Incorporated
NCT01208415
|
PRESERVE- Zenith® Iliac Branch Clinical Study Clinical Study to Evaluate
the Safety and Effectiveness of the Zenith® Branch Endovascular Graft-Iliac
Bifurcation |
- Aortoiliac or iliac aneurysm
- Unsuitable distal sealing site for a Zenith® iliac leg graft within
the common iliac artery on the intended side of Branch Graft implantation
|
| Coronary Bypass |
Alexander Kulik, MD
NCT02053909
|
Ticagrelor Antiplatelet Therapy to Reduce Graft Events and Thrombosis (TARGET
Trial): Does Ticagrelor Improve Graft Patency after Coronary Bypass? |
- Female and/or male aged 18 - 90 years
- Undergoing first time CABG with at least 1 saphenous vein graft, irrespective
of concurrent valve surgery
|
|
Medtronic
NCT # N/A
|
STOP Persistent AF |
- Symptomatic persistent AF defined as having continuous episode lasting
longer than 7 days but less than 6 months by consecutive ECG
- Failure or intolerance to at least one Class I or III antiarrhythmic drug
- Age 18 to 80
|
|
St. Jude Medical, Inc.
NCT # N/A
|
MultiPoint Pacing™ Post Market Study (MPP PMS) |
- Scheduled to receive new CRT implant or upgrade from an existing ICD/Pacemaker
implant with no prior LV lead placement
|